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Home >> Antibodies >> Recombinant Bax Antibody

Recombinant Bax Antibody [clone BAX/8960R] (V4648)

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  Catalog No Formulation Size Price (USD)  
Image V4648-100UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide 100 ug 519
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V4648-20UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide 20 ug 229
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V4648SAF-100UG 1 mg/ml in 1X PBS; BSA free, sodium azide free 100 ug 519
Microvalidated Recrabbitmono
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Availability 1-3 business days
Species Reactivity Human
Format Purified
Clonality Recombinant Rabbit Monoclonal
Isotype Rabbit IgG, kappa
Clone Name BAX/8960R
Purity Protein A/G affinity
UniProt Q07812
Localization Cytoplasm
Applications Immunohistochemistry (FFPE) : 1-2ug/ml for 30 min at RT
Limitations This recombinant Bax antibody is available for research use only.
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Description

Recognizes a protein of 21kDa, identified as the Bax protein. This mAb is highly specific to Bax and shows no cross-reaction with Bcl-2 or Bcl-X protein. Bcl-2 blocks cell death following a variety of stimuli. Bax has extensive amino acid homology with Bcl-2 and it homodimerizes and forms heterodimers with Bcl-2. Overexpression of Bax accelerates apoptotic death induced by cytokine deprivation in an IL-3 dependent cell line, and Bax also counters the death repressor activity of Bcl-2.

Application Notes

Optimal dilution of the recombinant Bax antibody should be determined by the researcher.

Immunogen

Recombinant full-length human BAX protein was used as the immunogen for the recombinant Bax antibody.

Storage

Aliquot the recombinant Bax antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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