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- Email: info@nsjbio.com
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Acts as a coactivator of transcriptional activity. Required to increase TGFB1/Smad-mediated transactivation. Acts through SMAD2, SMAD3 and SMAD4 to increase transcriptional activity. Increases phosphorylation of SMAD2 and SMAD3 on their C-terminal SSXS motif, possibly through recruitment of TGFBR1. Promotes the nuclear accumulation of SMAD2, SMAD3 and SMAD4 proteins. Binds to poly(A) RNA.
Titration of the RBPMS antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 166-193 from the human protein was used as the immunogen for this RBPMS antibody.
Aliquot the RBPMS antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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