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Home >> Antibodies >> RBPMS Antibody

RBPMS Antibody (F52135)

  Catalog No Formulation Size Price (USD)  
Image F52135-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 399
Image
F52135-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 185
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RBPMS antibody western blot analysis in NCI-H460 lysate.
Availability 1-3 business days
Species Reactivity Human
Predicted Reactivity Mouse
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Antigen affinity
UniProt Q93062
Applications Western blot : 1:1000
Limitations This RBPMS antibody is available for research use only.
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  • Applications : WB, IHC-P, FACS, Direct ELISA
    Reactivity : Human, Mouse, Rat

Description

Acts as a coactivator of transcriptional activity. Required to increase TGFB1/Smad-mediated transactivation. Acts through SMAD2, SMAD3 and SMAD4 to increase transcriptional activity. Increases phosphorylation of SMAD2 and SMAD3 on their C-terminal SSXS motif, possibly through recruitment of TGFBR1. Promotes the nuclear accumulation of SMAD2, SMAD3 and SMAD4 proteins. Binds to poly(A) RNA.

Application Notes

Titration of the RBPMS antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A portion of amino acids 166-193 from the human protein was used as the immunogen for this RBPMS antibody.

Storage

Aliquot the RBPMS antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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