- Tel: 858.663.9055
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
RBPJ Antibody / RBP-JK (F45603)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
 |
F45603-0.4ML | In 1X PBS, pH 7.4, with 0.09% sodium azide | 0.4 ml | 399 | |
|
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F45603-0.08ML | In 1X PBS, pH 7.4, with 0.09% sodium azide | 0.08 ml | 185 |
| Availability | 1-3 business days |
| Species Reactivity | Human |
| Format | Antigen affinity purified |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit Ig |
| Purity | Antigen affinity |
| UniProt | Q06330 |
| Applications | Western blot : 1:1000-2000 IHC (Paraffin) : 1:10-1:50 Immunofluorescence : 1:10-1:50 |
| Limitations | This RBPJ antibody is available for research use only. |
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Transcriptional regulator that plays a central role in Notch signaling, a signaling pathway involved in cell-cell communication that regulates a broad spectrum of cell-fate. determinations. Acts as a transcriptional repressor when it is not associated with Notch proteins. When associated with some Notch protein, it acts as a transcriptional activator that activates transcription of Notch target genes. Probably represses or activates transcription via the recruitment of chromatin remodeling complexes containing histone deacetylase or histone acetylase proteins, respectively. Specifically binds to the immunoglobulin kappa-type J segment recombination signal sequence.
Titration of the RBPJ antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 1-29 from the human protein was used as the immunogen for this RBPJ antibody.
Aliquot the RBPJ antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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