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Home >> Antibodies >> RAB7 Antibody

RAB7 Antibody (F51272)

  Catalog No Formulation Size Price (USD)  
Image F51272-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 399
Image
F51272-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 185
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RAB7 antibody flow cytometry analysis of K562 cells (bottom histogram) compared to a negative control (top histogram). FITC-conjugated goat-anti-rabbit secondary Ab was used for the analysis.
IHC analysis of FFPE human skeletal muscle stained with RAB7 antibody
Western blot analysis of RAB7 antibody and K562 lysate. Expected molecular weight ~23 kDa.
Availability 1-3 business days
Species Reactivity Human
Predicted Reactivity Mouse
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Antigen affinity
UniProt P51149
Localization Cytoplasmic
Applications Western blot : 1:1000
IHC (Paraffin) : 1:50-1:100
Flow Cytometry : 1:10-1:50
Limitations This RAB7 antibody is available for research use only.
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  • Applications : WB, IF, FACS
    Reactivity : Human, Mouse, Rat

Description

RAB family members are small, RAS-related GTP-binding proteins that are important regulators of vesicular transport. Each RAB protein targets multiple proteins that act in exocytic / endocytic pathways. RAB7 is a RAB family member that regulates vesicle traffic in the late endosomes and also from late endosomes to lysosomes. This protein is also involved in the cellular vacuolation of the VacA cytotoxin of Helicobacter pylori.

Application Notes

Titration of the RAB7 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A portion of amino acids 176-204 from human RAB7A was used as the immunogen for this RAB7 antibody.

Storage

Aliquot the RAB7 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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