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- Tel: 858.663.9055
- Email: info@nsjbio.com
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Recognizes a single protein of 33-34kDa, identified as the prostate specific antigen (PSA). This mAb is highly specific to PSA and stains prostatic secretory and ductal epithelium in both normal and neoplastic tissues. PSA is a chymotrypsin-like serine protease (kallikrein family) exclusively produced by the prostate epithelium, and abundant in seminal fluid. PSA can be detected in the sera of patients with prostatic carcinoma. It is predominantly complexed to a liver-derived serine protease inhibitor, alpha-1-antichymotrypsin (ACT). A higher proportion of serum PSA is complexed to ACT in prostate cancer than in benign prostate hyperplasia. This mAb makes an excellent pair with mAb 1A7G6B6 for PSA tests.
Optimal dilution of the Prostate Specific Antigen antibody should be determined by the researcher.
A recombinant partial protein sequence (within amino acids 150-250) from the human protein was used as the immunogen for the Prostate Specific Antigen antibody.
Aliquot the Prostate Specific Antigen antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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