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Prolactin, also known as luteotropic hormone (LTH) is a protein that in humans is encoded by the PRL gene. Prolactin is a peptide hormone discovered by Henry Friesen. Although it is perhaps best known for its role in lactation, it already existed in the oldest known vertebrates—fishes—where its most important functions were probably related to control of water and salt balance. Prolactin also acts in a cytokine-like manner and as an important regulator of the immune system. It has important cell cycle related functions as a growth-, differentiating- and anti-apoptotic factor. As a growth factor binding to cytokine like receptors it has also profound influence on hematopoiesis, angiogenesis and is involved in the regulation of blood clotting through several pathways.
The stated application concentrations are suggested starting amounts. Titration of the Prolactin antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Mouse partial recombinant protein (AA 30-226) was used as the immunogen for this Prolactin antibody.
After reconstitution, the Prolactin antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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