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- Tel: 858.663.9055
- Email: info@nsjbio.com
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Protein arginine N-methyltransferases, such as CARM1, catalyze the transfer of a methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins to form methylated arginine derivatives and S-adenosyl-L-homocysteine. Protein arginine methylation has been implicated in signal transduction, metabolism of nascent pre-RNA, and transcriptional activation (Frankel et al., 2002 [PubMed 11724789]).
Titration of the PRMT4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 346-377 from the human protein was used as the immunogen for this PRMT4 antibody.
Aliquot the PRMT4 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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