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Home >> Antibodies >> PRMT4 Antibody

PRMT4 Antibody (F41369)

  Catalog No Formulation Size Price (USD)  
Image F41369-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 399
Image
F41369-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 185
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IHC testing of PRMT4 antibody and FFPE human prostate carcinoma.
PRMT4 antibody western blot analysis in Jurkat lysate.
PRMT4 antibody flow cytometric analysis of Jurkat cells (green) compared to a negative control (blue). FITC-conjugated donkey-anti-rabbit secondary Ab was used for the analysis.
Availability 1-3 business days
Species Reactivity Human
Predicted Reactivity Mouse, Rat
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Antigen affinity
UniProt Q86X55
Applications Western blot : 1:1000
IHC (Paraffin) : 1:50-1:100
Flow Cytometry : 1:10-1:50
Limitations This PRMT4 antibody is available for research use only.
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Description

Protein arginine N-methyltransferases, such as CARM1, catalyze the transfer of a methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins to form methylated arginine derivatives and S-adenosyl-L-homocysteine. Protein arginine methylation has been implicated in signal transduction, metabolism of nascent pre-RNA, and transcriptional activation (Frankel et al., 2002 [PubMed 11724789]).

Application Notes

Titration of the PRMT4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A portion of amino acids 346-377 from the human protein was used as the immunogen for this PRMT4 antibody.

Storage

Aliquot the PRMT4 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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