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Home >> Antibodies >> PRMT3 Antibody

PRMT3 Antibody (F40452)

  Catalog No Formulation Size Price (USD)  
Image F40452-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 399
Image
F40452-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 185
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Western blot analysis of PRMT3 antibody and whole HL-60 cell lysate. Predicted molecular weight: 55-60 kDa.
IHC analysis of FFPE human breast carcinoma tissue stained with the PRMT3 antibody
IHC analysis of FFPE human prostate carcinoma tissue stained with PRMT3 antibody
Availability 1-3 business days
Species Reactivity Human
Predicted Reactivity Mouse
Format Purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Purified
UniProt O60678
Applications Western blot : 1:1000
IHC (Paraffin) : 1:50-1:100
Limitations This PRMT3 antibody is available for research use only.
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Description

Arginine methylation is an irreversible post translational modification which has only recently been linked to protein activity. At least three types of PRMT enzymes have been identified in mammalian cells. These enzymes have been shown to have essential regulatory functions by methylation of key proteins in several fundamental areas. These protein include nuclear proteins, IL enhancer binding factor, nuclear factors, cell cycle proteins, signal transduction proteins, apoptosis proteins, and viral proteins. The mammalian PRMT family currently consists of 7 members that share two large domains of homology. Outside of these domains, epitopes were identified and antibodies against all 7 PRMT members have been developed.

Application Notes

Titration of the PRMT3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A portion of amino acids 460-491 from the human protein was used as the immunogen for this PRMT3 antibody.

Storage

Aliquot the PRMT3 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Cross
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