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Home >> Antibodies >> PRMT2 Antibody

PRMT2 Antibody (F40440)

  Catalog No Formulation Size Price (USD)  
Image F40440-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 399
Image
F40440-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 185
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IHC analysis of FFPE human breast carcinoma tissue stained with the PRMT2 antibody
The PRMT2 antibody used in western blot to detect PRMT2 in HL-60 cell lysate
Western blot analysis of PRMT2 antibody and 293 cell lysate either nontransfected (Lane 1) or transiently transfected (2) with the PRMT2 gene.
Availability 1-3 business days
Species Reactivity Human
Format Purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Purified
UniProt P55345
Applications IHC (Paraffin) : 1:50-1:100
Western blot : 1:1000
Limitations This PRMT2 antibody is available for research use only.
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Description

Arginine methylation is an irreversible post translational modification which has only recently been linked to protein activity. At least three types of PRMT enzymes have been identified in mammalian cells. These enzymes have been shown to have essential regulatory functions by methylation of key proteins in several fundamental areas. These protein include nuclear proteins, IL enhancer binding factor, nuclear factors, cell cycle proteins, signal transduction proteins, apoptosis proteins, and viral proteins. The mammalian PRMT family currently consists of 7 members that share two large domains of homology. Outside of these domains, epitopes were identified and antibodies against all 7 PRMT members have been developed.

Application Notes

Titration of the PRMT2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A portion of amino acids 22-53 from the human protein was used as the immunogen for this PRMT2 antibody.

Storage

Aliquot the PRMT2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Cross
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