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Home >> Antibodies >> PON2 Antibody / Paraoxonase 2

PON2 Antibody / Paraoxonase 2 (R32234)

  Catalog No Formulation Size Price (USD)  
Image R32234 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 429
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Western blot testing of human HeLa cell lysate with PON2 antibody. Expected/observed molecular weight ~39 kDa.
Availability 1-3 business days
Species Reactivity Human
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Antigen affinity
Buffer Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide
UniProt Q15165
Applications Western blot : 0.1-0.5ug/ml
Limitations This PON2 antibody is available for research use only.
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Description

PON2 is an enzyme that in humans is encoded by the PON2 gene. It is mapped to 7q21.3. This gene encodes a member of the paraoxonase gene family, which includes three known members located adjacent to each other on the long arm of chromosome 7. The encoded protein is ubiquitously expressed in human tissues, membrane-bound, and may act as a cellular antioxidant, protecting cells from oxidative stress. Hydrolytic activity against acylhomoserine lactones and important bacterial quorum-sensing mediators suggests the encoded protein may also play a role in defense responses to pathogenic bacteria. Mutations in this gene may be associated with vascular disease and a number of quantitative phenotypes related to diabetes.

Application Notes

Optimal dilution of the PON2 antibody should be determined by the researcher.

Immunogen

Amino acids AHEIHVLEKHTNMNLTQLKVLELDTLVDNLSID of human PON2 were used as the immunogen for the PON2 antibody.

Storage

After reconstitution, the PON2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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