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The enzyme cleaves Lys-Arg and Arg-Ser bonds. It activates, in a reciprocal reaction, factor XII after its binding to a negatively charged surface. It also releases bradykinin from HMW kininogen and may also play a role in the renin-angiotensin system by converting prorenin into renin. [UniProt]
Optimal dilution of the Plasma Kallikrein antibody should be determined by the researcher.
A synthetic peptide specific to human Plasma Kallikrein / KLKB1 was used as the immunogen for the Plasma Kallikrein antibody.
Store the Plasma Kallikrein antibody at -20oC.
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