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Home >> Antibodies >> Phospho-TrkA Antibody (pY791)

Phospho-TrkA Antibody (pY791) (F48462)

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  Catalog No Formulation Size Price (USD)  
Image F48462-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 399
Image
F48462-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 185
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Dot blot analysis of phospho-TrkA antibody. 50ng of phos-peptide or nonphos-peptide per dot were spotted.
Dot blot analysis of phospho-TrkA antibody. 50ng of phos-peptide or nonphos-peptide per dot were spotted.
Availability 1-3 business days
Species Reactivity Human
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Antigen affinity
UniProt P04629
Applications Dot blot : 1:500
Limitations This phospho-TrkA antibody is available for research use only.
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Description

TrkA is a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in the TrkA gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, mental retardation and cancer.

Application Notes

Titration of the phospho-TrkA antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

This phospho-TrkA antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pY791 of human TrkA.

Storage

Aliquot the phospho-TrkA antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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