- Tel: 858.663.9055
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
Pf4 Antibody / Platelet factor 4 (R32449)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
 |
R32449 | 0.5mg/ml if reconstituted with 0.2ml sterile DI water | 100 ug | 429 |
| Availability | 1-3 business days |
| Species Reactivity | Mouse |
| Format | Antigen affinity purified |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit IgG |
| Purity | Antigen affinity |
| Buffer | Lyophilized from 1X PBS with 2% Trehalose |
| UniProt | Q9Z126 |
| Localization | Cytoplasmic, membranous |
| Applications | Western blot : 0.5-1ug/ml IHC (FFPE) : 1-2ug/ml ELISA : 0.1-0.5ug/ml (mouse protein tested); request BSA-free format for coating |
| Limitations | This Pf4 antibody is available for research use only. |
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Platelet factor 4 (PF4) is a small cytokine belonging to the CXC chemokine family that is also known as chemokine (C-X-C motif) ligand 4 (CXCL4). By in situ hybridization, the CXCL4 gene is mapped to chromosome 4q12-q21. Its major physiologic role appears to be neutralization of heparin-like molecules on the endothelial surface of blood vessels, thereby inhibiting local antithrombin III activity and promoting coagulation. As a strong chemoattractant for neutrophils and fibroblasts, PF4 probably has a role in inflammation and wound repair.
Optimal dilution of the Pf4 antibody should be determined by the researcher.
Amino acids V30-S105 from the mouse protein were used as the immunogen for the Pf4 antibody.
Prior to reconstitution, store at 4oC. After reconstitution, the Pf4 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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