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- Tel: 858.663.9055
- Email: info@nsjbio.com
The PER3 gene encodes the period circadian protein homolog 3 protein in humans. This gene is a member of the Period family of genes and is expressed in a circadian pattern in the suprachiasmatic nucleus, the primary circadian pacemaker in the mammalian brain. Genes in this family encode components of the circadian rhythms of locomotor activity, metabolism, and behavior. This gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene have been linked to sleep disorders. Multiple transcript variants encoding different isoforms have been found for this gene.
Optimal dilution of the PER3 antibody should be determined by the researcher.
A recombinant human partial protein corresponding to amino acids Q1085-D1199 was used as the immunogen for the PER3 antibody.
After reconstitution, the PER3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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