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Home >> Antibodies >> PD-L2 Antibody

PD-L2 Antibody [clone CDLA273-1] (V7546)

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  Catalog No Formulation Size Price (USD)  
Image V7546-100UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide 100 ug 519
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V7546-20UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide 20 ug 229
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V7546SAF-100UG 1 mg/ml in 1X PBS; BSA free, sodium azide free 100 ug 519
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Western blot testing of 1) human Raji and 2) mouse RAW264.7 cell lysate with PD-L2 antibody (clone CDLA273-1). Expected molecular weight: 31-60 kDa depending on glycosylation level.
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Western blot testing of 1) human Raji and 2) mouse RAW264.7 cell lysate with PD-L2 antibody (clone CDLA273-1). Expected molecular weight: 31-60 kDa depending on glycosylation level.
Flow cytometry testing of human Jurkat cells with PD-L2 antibody (clone CDLA273-1); Red=isotype control, Blue= PD-L2 antibody.
Immunofluorescent staining of human Jurkat cells with PD-L2 antibody (green, clone CDLA273-1) and DAPI nuclear stain (blue). HIER: steam section in pH6 citrate buffer for 20 min.
Availability 1-3 business days
Species Reactivity Human
Format Purified
Clonality Monoclonal (mouse origin)
Isotype Mouse IgG1, kappa
Clone Name CDLA273-1
Purity Protein G affinity chromatography
UniProt Q9BQ51
Localization Cytoplasm, cell surface
Applications Western blot : 1-2ug/ml
Flow cytometry : 1-2ug/10^6 cells
Immunofluorescence : 1-2ug/ml
Limitations This PD-L2 antibody is available for research use only.
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Description

PD-L2/PDCD1LG2 is involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production. [UniProt]

Application Notes

Optimal dilution of the PD-L2 antibody should be determined by the researcher.

Immunogen

A recombinant fragment of human PD-L2 protein within amino acids 27-220 was used as the immunogen for the PD-L2 antibody.

Storage

Store the PD-L2 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

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