- Tel: 858.663.9055
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
PD-L1 Antibody / C-Terminal Region (F54219)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
 |
F54219-0.2ML | In 1X PBS, pH 7.4, with 0.09% sodium azide | 0.2 ml | 399 | |
|
|
F54219-0.05ML | In 1X PBS, pH 7.4, with 0.09% sodium azide | 0.05 ml | 185 |
| Availability | 1-3 business days |
| Species Reactivity | Human |
| Format | Antigen affinity purified |
| Clonality | Polyclonal |
| Isotype | Rabbit Ig |
| Purity | Peptide affinity purified |
| UniProt | Q9NZQ7 |
| Applications | Western Blot : 1:1000 |
| Limitations | This PD-L1 antibody is available for research use only. |
|
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Programmed cell death 1 ligand 1 (PD-L1), also called CD274, is involved in the costimulatory signal, essential for T- cell proliferation and production of IL10 and IFNG, in an IL2- dependent and a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation and cytokine production.
The stated application concentrations are suggested starting points. Titration of the PD-L1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 252-290 from the C-terminal region of the human protein was used as the immunogen for the PD-L1 antibody.
Aliquot the PD-L1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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