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- Tel: 858.663.9055
- Email: info@nsjbio.com
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The protein encoded by this gene belongs to the subtilisin-like proprotein convertase family. The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products. This encoded protein is a calcium-dependent serine endoprotease that can cleave precursor protein at their paired basic amino acid processing sites. Some of its substrates are - transforming growth factor beta related proteins, proalbumin, and von Willebrand factor. This gene is thought to play a role in tumor progression. Alternatively spliced transcript variants encoding different isoforms have been identified.
Titration of the PCSK6 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 659-688 from the human protein was used as the immunogen for this PCSK6 antibody.
Aliquot the PCSK6 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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