PAX7 Antibody PAX7/497 | V2217 NSJ Bioreagents

	Catalog No	Formulation	Size	Price (USD)
	V2217-100UG	0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide	100 ug	519
Formulation
	V2217-20UG	0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide	20 ug	229
Formulation
	V2217SAF-100UG	1 mg/ml in 1X PBS; BSA free, sodium azide free	100 ug	519
Formulation

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Western blot testing of human HeLa cell lysate with PAX7 antibody (clone PAX7/497). Expected molecular weight: 55-57 kDa.

Species Reactivity	Human, Mouse, Rat
Format	Purified
Clonality	Monoclonal (mouse origin)
Isotype	Mouse IgG1, kappa
Clone Name	PAX7/497
Purity	Protein G affinity chromatography
Buffer	1X PBS, pH 7.4
Gene ID	5081
Localization	Nuclear
Applications	Immunofluorescence : 0.5-1ug/ml Flow cytometry : 0.5-1ug/10^6 cells Western blot : 0.5-1ug/ml
Limitations	This PAX7 antibody is available for research use only.
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Description

The PAX gene family of nuclear transcription factors is comprised of nine members that function during embryogenesis to regulate the temporal and position-dependent differentiation of cells. In addition, the family is involved in a variety of signal transduction pathways in the adult organism. Mutations in the PAX family of proteins have been linked to disease and cancer in humans. PAX7 is a protein specifically expressed in cultured satellite cell- derived myoblasts. In situ hybridization reveals that PAX7 is also expressed in satellite cells residing in adult muscle. A chromosomal aberration in the gene encoding PAX7 causes rhabdomyosarcoma 2 (RMS2) (also called alveolar rhabdomyosarcoma).

Application Notes

The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the antibody to be titered up or down for optimal performance.