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Home >> Antibodies >> PAX6 Antibody

PAX6 Antibody (F52936)

  Catalog No Formulation Size Price (USD)  
Image F52936-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 399
Image
F52936-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 185
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Western blot analysis of lysate from HepG2 cell line using PAX6 antibody; Ab was diluted at 1:1000. Predicted molecular weight ~48kDa.
Availability 1-3 business days
Species Reactivity Human
Predicted Reactivity Mouse, Bovine, Zebrafish
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Antigen affinity
UniProt P26367
Applications Western blot : 1:1000
Limitations This PAX6 antibody is available for research use only.
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Description

Transcription factor with important functions in the development of the eye, nose, central nervous system and pancreas. Required for the differentiation of pancreatic islet alpha cells (By similarity). Competes with PAX4 in binding to a common element in the glucagon, insulin and somatostatin promoters. Regulates specification of the ventral neuron subtypes by establishing the correct progenitor domains (By similarity). Isoform 5a appears to function as a molecular switch that specifies target genes.

Application Notes

Titration of the PAX6 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

This PAX6 antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 183-214 amino acids from the Central region of human PAX6.

Storage

Aliquot the PAX6 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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