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Home >> Antibodies >> PAK6 Antibody

PAK6 Antibody (F41956)

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  Catalog No Formulation Size Price (USD)  
Image F41956-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 399
Image
F41956-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 185
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PAK6 antibody western blot analysis in K562 lysate.
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PAK6 antibody western blot analysis in K562 lysate.
PAK6 antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue.
Confocal immunofluorescent analysis of PAK6 antibody with U-251MG cells followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used as a nuclear counterstain (blue).
Availability 1-3 business days
Species Reactivity Human
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Antigen affinity
UniProt Q9NQU5
Applications Western blot : 1:1000
IHC (Paraffin) : 1:10-1:50
Immunofluorescence : 1:10-1:50
Limitations This PAK6 antibody is available for research use only.
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Description

This gene encodes a member of the p21-activated kinase (PAK) family. The proteins of this family are Rac/Cdc42-associated Ste20-like Ser/Thr protein kinases, characterized by a highly conserved amino-terminal Cdc42/Rac interactive binding (CRIB) domain and a carboxyl-terminal kinase domain. PAK kinases are implicated in the regulation of a number of cellular processes, including cytoskeleton rearrangement, apoptosis and the MAP kinase signaling pathway. The protein encoded by this gene was found to interact with androgen receptor (AR), which is a steroid hormone-dependent transcription factor that is important for male sexual differentiation and development. This gene was found to be highly expressed in testis and prostate tissues and the encoded protein was shown to cotranslocate into the nucleus with AR in response to androgen. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq].

Application Notes

Titration of the PAK6 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A portion of amino acids 268-297 from the human protein was used as the immunogen for this PAK6 antibody.

Storage

Aliquot the PAK6 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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