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- Email: info@nsjbio.com
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The SERPINE1 gene encodes a member of the serine proteinase inhibitor (serpin) superfamily. This member is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), and hence is an inhibitor of fibrinolysis. Defects in this gene are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency), and high concentrations of the gene product are associated with thrombophilia.
Optimal dilution of the PAI-1 antibody should be determined by the researcher.
A synthetic peptide specific to human PAI1 / SERPINE1 was used as the immunogen for the PAI-1 antibody.
Store the PAI-1 antibody at -20oC.
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