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Home >> Antibodies >> PAI-1 Antibody / Plasminogen activator inhibitor 1

PAI-1 Antibody / Plasminogen activator inhibitor 1 [clone ABHG-19] (RQ5107)

  Catalog No Formulation Size Price (USD)  
Image RQ5107 Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA 100 ul 429
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Western blot testing of human HepG2 cell lysate with PAI-1 antibody. Predicted molecular weight ~45 kDa.
Availability 1-2 weeks
Species Reactivity Human
Format Purified
Clonality Rabbit Monoclonal
Isotype Rabbit IgG
Clone Name ABHG-19
Purity Affinity purified
UniProt P05121
Applications Western blot : 1:500-1:1000
Limitations This PAI-1 antibody is available for research use only.
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Description

The SERPINE1 gene encodes a member of the serine proteinase inhibitor (serpin) superfamily. This member is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), and hence is an inhibitor of fibrinolysis. Defects in this gene are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency), and high concentrations of the gene product are associated with thrombophilia.

Application Notes

Optimal dilution of the PAI-1 antibody should be determined by the researcher.

Immunogen

A synthetic peptide specific to human PAI1 / SERPINE1 was used as the immunogen for the PAI-1 antibody.

Storage

Store the PAI-1 antibody at -20oC.

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