- Tel: 858.663.9055
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
PACSIN2 Antibody [clone 1735CT116.76.60] (F53980)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
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F53980-0.2ML | In 1X PBS, pH 7.4, with 0.09% sodium azide | 0.2 ml | 399 | |
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F53980-0.05ML | In 1X PBS, pH 7.4, with 0.09% sodium azide | 0.05 ml | 185 |
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| Availability | 1-3 business days |
| Species Reactivity | Human, Mouse |
| Format | Purified |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Mouse IgG1, kappa |
| Clone Name | 1735CT116.76.60 |
| Purity | Protein G affinity chromatography |
| UniProt | Q9UNF0 |
| Localization | Cytoplasmic |
| Applications | Western blot : 1:1000-1:2000 |
| Limitations | This PACSIN2 antibody is available for research use only. |
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Protein kinase C and casein kinase substrate in neurons protein 2 is a lipid-binding protein that is able to promote the tubulation of the phosphatidic acid-containing membranes it preferentially binds. Plays a role in intracellular vesicle- mediated transport. Involved in the endocytosis of cell-surface receptors like the EGF receptor, contributing to its internalization in the absence of EGF stimulus. May also play a role in the formation of caveolae at the cell membrane. Recruits DNM2 to caveolae, and thereby plays a role in caveola-mediated endocytosis.
Titration of the PACSIN2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A partial recombinant protein corresponding to amino acids 250-486 from the human protein was used as the immunogen for the PACSIN2 antibody.
Aliquot the PACSIN2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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