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Cyclins are important in regulating the cell cycle through their formation of enzymatic complexes with various cyclin-dependent kinases. P19(INK4d) also kowns as cyclin-dependent kinase inhibitor 2D, is one of the novel members of the mouse INK4 gene family. Okuda et al.(1995) described the cloning of the human INK4d gene(CDKN2D). The predicted 166-amino acid protein is 86% identical to the mouse protein and about 45% identical to other human INK4 family members.
The stated application concentrations are suggested starting amounts. Titration of the p19INK4d antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Recombinant human p19INK4d was used as the immunogen for this p19INK4d antibody.
After reconstitution, the p19INK4d antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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