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- Email: info@nsjbio.com
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Acts as a negative regulator of the proliferation of normal cells by interacting strongly with CDK4 and CDK6. This inhibits their ability to interact with cyclins D and to phosphorylate the retinoblastoma protein.
Titration of the p16INK4a antibody may be required due to differences in protocols and secondary/substrate sensitivity.
This p16INK4a antibody was produced from a rabbit immunized with a KLH conjugated synthetic peptide between 145-176 amino acids from human p16-INK4a.
Aliquot the p16INK4a antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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