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Home >> Antibodies >> p120 Catenin Antibody / CTNND1

p120 Catenin Antibody / CTNND1 [clone GI-3] (RQ4764)

  Catalog No Formulation Size Price (USD)  
Image RQ4764 Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA 100 ul 429
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Western blot testing of human HeLa cell lysate with p120 Catenin antibody. Predicted molecular weight of isoform 1: 102-108 kDa and isoform 2: 95-102 kDa.
Availability 1-2 weeks
Species Reactivity Human
Format Purified
Clonality Rabbit Monoclonal
Isotype Rabbit IgG
Clone Name GI-3
Purity Affinity purified
UniProt O60716
Applications Western blot : 1:500-1:2000
Limitations This p120 Catenin antibody is available for research use only.
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Description

p120 Catenin binds to and inhibits the transcriptional repressor ZBTB33, which may lead to activation of target genes of the Wnt signaling pathway (By similarity). Associates with and regulates the cell adhesion properties of both C-, E- and N-cadherins, being critical for their surface stability. Implicated both in cell transformation by SRC and in ligand-induced receptor signaling through the EGF, PDGF, CSF-1 and ERBB2 receptors. Promotes GLIS2 C-terminal cleavage. [UniProt]

Application Notes

Optimal dilution of the p120 Catenin antibody should be determined by the researcher.

Immunogen

A synthetic peptide specific to human Catenin delta 1 / p120 Catenin / CTNND1 was used as the immunogen for the p120 Catenin antibody.

Storage

Store the p120 Catenin antibody at -20oC.

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