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Home >> Antibodies >> OGT Antibody

OGT Antibody (F49797)

  Catalog No Formulation Size Price (USD)  
Image F49797-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 399
Image
F49797-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 185
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Western blot analysis of OGT antibody and mouse bladder tissue lysate. Expected/observed molecular weight: 110-117 kDa.
IHC analysis of FFPE human brain tissue stained with OGT antibody
Availability 1-3 business days
Species Reactivity Human, Mouse
Predicted Reactivity Rat, Pig, Rabbit
Format Purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Purified
UniProt O15294
Localization Nuclear, cytoplasmic
Applications Western blot : 1:1000
IHC (Paraffin) : 1:50-1:100
Limitations This OGT antibody is available for research use only.
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Description

O-linked N-acetylglucosamine (O-GlcNAc) transferase (OGT) catalyzes the addition of a single N-acetylglucosamine in O-glycosidic linkage to serine or threonine residues. Since both phosphorylation and glycosylation compete for similar serine or threonine residues, the two processes may compete for sites, or they may alter the substrate specificity of nearby sites by steric or electrostatic effects. The protein contains nine tetratricopeptide repeats and a putative bipartite nuclear localization signal.

Application Notes

Titration of the OGT antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A portion of amino acids 1017-1046 from the human protein was used as the immunogen for this OGT antibody.

Storage

Aliquot the OGT antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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