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Home >> Antibodies >> NMU Antibody / Neuromedin-U

NMU Antibody / Neuromedin-U (RQ4097)

  Catalog No Formulation Size Price (USD)  
Image RQ4097 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 429
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Western blot testing of 1) rat kidney and 2) mouse kidney lysate with NMU antibody at 0.5ug/ml. Expected molecular weight: 20-25 kDa.
Availability 1-3 business days
Species Reactivity Mouse, Rat
Predicted Reactivity Human
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Antigen affinity purified
Buffer Lyophilized from 1X PBS with 2% Trehalose and 0.025% sodium azide
UniProt P48645
Applications Western Blot : 0.5-1ug/ml
Limitations This NMU antibody is available for research use only.
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Description

Neuromedin U (NMU) is a neuropeptide with potent activity on smooth muscle, which was isolated first from porcine spinal cord and later from other species. It is a member of the neuromedin family of neuropeptides. The encoded protein is a precursor that is proteolytically processed to generate a biologically active neuropeptide that plays a role in pain, stress, immune-mediated inflammatory diseases and feeding regulation. Increased expression of this gene was observed in renal, pancreatic and lung cancers. Alternative splicing results in multiple transcript variants encoding different isoforms. Some of these isoforms may undergo similar processing to generate the mature peptide.

Application Notes

Optimal dilution of the NMU antibody should be determined by the researcher.

Immunogen

Amino acids FRVDEEFQSPFASQSRGYFLFRPRN from the human protein were used as the immunogen for the NMU antibody.

Storage

After reconstitution, the NMU antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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