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Home >> Antibodies >> NLRC4 Antibody / CARD12

NLRC4 Antibody / CARD12 (R32329)

  Catalog No Formulation Size Price (USD)  
Image R32329 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 429
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Western blot testing of 1) human 22RV1, 2) RH35 and 3) mouse NIH3T3 lysate with NLRC4 antibody. Expected/observed molecular weight ~116 kDa.
Availability 1-3 business days
Species Reactivity Human, Mouse, Rat
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Antigen affinity
Buffer Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide
UniProt Q9NPP4
Applications Western blot : 0.1-0.5ug/ml
Limitations This NLRC4 antibody is available for research use only.
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Description

NLR family CARD domain-containing protein 4, also known as CARD12, is a protein that in humans is encoded by the NLRC4 gene. It is mapped to 2p22.3. This gene encodes a member of the caspase recruitment domain-containing NLR family. Family members play essential roles in innate immune response to a wide range of pathogenic organisms, tissue damage and other cellular stresses. Mutations in this gene result in autoinflammation with infantile enterocolitis. Alternative splicing results in multiple transcript variants.

Application Notes

Optimal dilution of the NLRC4 antibody should be determined by the researcher.

Immunogen

Amino acids KILAQNLHNLVKLSILDLSENYLEKDGNEALHELIDR of human NLRC4/CARD12 were used as the immunogen for the NLRC4 antibody.

Storage

After reconstitution, the NLRC4 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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