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Home >> Antibodies >> NKX2.8 Antibody

NKX2.8 Antibody [clone NKX28/2548] (V7803)

  Catalog No Formulation Size Price (USD)  
Image V7803-100UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide 100 ug 519
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V7803-20UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide 20 ug 229
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V7803SAF-100UG 1 mg/ml in 1X PBS; BSA free, sodium azide free 100 ug 519
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Western blot testing of human PC-3 and MCF-7 cell lysate with NKX2.8 antibody. Predicted molecular weight ~26 kDa, commonly observed at 26-34 kDa.
SDS-PAGE analysis of purified, BSA-free NKX2.8 antibody as confirmation of integrity and purity.
Availability 1-3 business days
Species Reactivity Human
Format Purified
Clonality Monoclonal (mouse origin)
Isotype Mouse IgG1, kappa
Clone Name NKX28/2548
Purity Protein G affinity chromatography
UniProt O15522
Applications ELISA (order BSA-free format for coating) :
Flow cytometry : 1-2ug/10^6 cells in 0.1ml
Western blot : 1-2ug/ml
Limitations This NKX2.8 antibody is available for research use only.
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Description

The protein encoded by this gene is a homeobox-containing developmental regulator associated with liver development. The encoded protein binds to the alpha-fetoprotein (AFP) gene promoter and increases the expression of AFP. This gene is overexpressed in some lung cancers and is linked to poor patient survival, possibly due to its resistance to cisplatin. This gene is aberrantly methylated in pancreatic cancer, deleted in squamous cell lung carcinomas, and acts as a tumor suppressor in esophageal cancer. Mutations in this gene may also be a cause of neural tube defects.

Application Notes

Optimal dilution of the NKX2.8 antibody should be determined by the researcher.

Immunogen

A recombinant human partial protein (amino acids 10-123) was used as the immunogen for the NKX2.8 antibody.

Storage

Store the NKX2.8 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

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