- Tel: 858.663.9055
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
NKIRAS1 Antibody [clone NRAS285] (N1127)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
 |
N1127-100UG | 0.5 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide | 100 ug | 429 | |
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N1127-25UG | 0.5 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide | 25 ug | 219 |
|
| Species Reactivity | Human, Mouse, Rat |
| Format | Purified |
| Clonality | Monoclonal (mouse origin) |
| Isotype | Mouse IgG1, kappa |
| Clone Name | NRAS285 |
| Purity | Protein G purified antibody |
| Buffer | 1X PBS, pH 7.4 |
| UniProt | Q9NYS0 |
| Gene ID | 28512 |
| Applications | Western blot : 5-10ug/ml |
| Limitations | This NKIRAS1 antibody is available for research use only. |
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NKIRAS1 is part of the Ras family and GTPase superfamily of proteins. Unlike other family members which have a glycine and glutamine residue at positions 13 and 65, NKIRAS1 (and 2) has leucines in these positions.
NKIRAS1 is a regulator of NF-kB activity via its inhibition of IkB (NFKBIB) degradation. IkB complexes with NF-kB, preventing nuclear translocation and subsequent signaling. By preventing or reducing IkB degradation, NKIRAS1 blocks NF-kB signaling activity.
Provided assay concentrations are suggestions only, NKIRAS1 antibody titration may be required for optimal results.
A recombinant protein fragment from the central region of NKIRAS1 was used as the immunogen for this antibody.
Aliquot the NKIRAS1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
kB-Ras1, I-kappa-B-interacting Ras-like Protein 1, NFKB inhibitor interacting Ras-like 1, KappaB-ras1
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