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Home >> Antibodies >> NFKB1 Antibody

NFKB1 Antibody (R31224)

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  Catalog No Formulation Size Price (USD)  
Image R31224 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 429
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Western blot testing of NFKB1 antibody and 1. HeLa and 2. Jurkat cell lysate. Expected molecular weight: 50 kDa / 105 kDa.
Western blot testing of NFKB1 antibody and 1. HeLa and 2. Jurkat cell lysate. Expected molecular weight: 50 kDa / 105 kDa.
Availability 1-3 business days
Species Reactivity Human, Mouse, Rat
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Antigen affinity
Buffer Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide/thimerosal
UniProt P19838
Applications Western blot : 0.5-1ug/ml
Limitations This NFKB1 antibody is available for research use only.
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Description

Nuclear factor NF-kappa-B p105/p50, also called EBP-1 is a protein that in humans is encoded by the NFKB1 gene. By fluorescence in situ hybridization, the gene was assigned to human chromosome 4q24. NF-kappa-B is a pleiotropic transcription factor present in almost all cell types and is the endpoint of a series of signal transduction events that are initiated by a vast array of stimuli related to many biological processes such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NFKB1 appears to have dual functions such as cytoplasmic retention of attached NF-kappa-B proteins by p105 and generation of p50 by a cotranslational processing.

Application Notes

The stated application concentrations are suggested starting amounts. Titration of the NFKB1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

An amino acid sequence from the N-terminus of human NFkB p105/p50 (KELIRQAALQQTKEMD) was used as the immunogen for this NFKB1 antibody.

Storage

After reconstitution, the NFKB1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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