• Tel: 858.663.9055
  • SeparatorEmail: info@nsjbio.com
  • Tel: 858.663.9055
  • Email: info@nsjbio.com
Order
Home >> Antibodies >> NFAT2 Antibody / NFATC1 (isoforms A/B/C)

NFAT2 Antibody / NFATC1 (isoforms A/B/C) (R32829)

NSJ bio Image Pdf Image
  Catalog No Formulation Size Price (USD)  
Image R32829 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 429
Bulk quote request
Western blot testing of 1) mouse thymus and 2) human 22RV1 lysate with NFAT2 antibody at 0.5ug/ml. Predicted molecular weight: ~77 kDa (isoform A), ~88 kDa (isoform B), ~101 kDa (isoform C).
›
Western blot testing of 1) mouse thymus and 2) human 22RV1 lysate with NFAT2 antibody at 0.5ug/ml. Predicted molecular weight: ~77 kDa (isoform A), ~88 kDa (isoform B), ~101 kDa (isoform C).
Flow cytometry testing of human THP-1 cells with NFAT2 antibody at 1ug/10^6 cells (blocked with goat sera); Red=cells alone, Green=isotype control, Blue=NFAT2 antibody.
Flow cytometry testing of human MCF-7 cells with NFAT2 antibody at 1ug/10^6 cells (blocked with goat sera); Red=cells alone, Green=isotype control, Blue=NFAT2 antibody.
Flow cytometry testing of human HeLa cells with NFAT2 antibody at 1ug/10^6 cells (blocked with goat sera); Red=cells alone, Green=isotype control, Blue=NFAT2 antibody.
Flow cytometry testing of human Jurkat cells with NFAT2 antibody at 1ug/10^6 cells (blocked with goat sera); Red=cells alone, Green=isotype control, Blue=NFAT2 antibody.
Availability 1-3 business days
Species Reactivity Human, Mouse, Rat
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Antigen affinity
Buffer Lyophilized from 1X PBS with 2.5% BSA, 0.025% sodium azide
UniProt O95644
Localization Cytoplasmic, nuclear
Applications Western Blot : 0.5-1ug/ml
Flow Cytometry : 1-3ug/10^6 cells
Direct ELISA (human recombinant protein : 0.1-0.5ug/ml (BSA-free formulation available)
Limitations This NFAT2 antibody is available for research use only.
Review this product on BioCompare and get a $20 Amazon gift card

Related Products

Description

NFATC1 (Nuclear factor of activated T-cells, cytoplasmic 1), also known as NFATC or NFAT2, is a protein that in humans is encoded by the NFATC1 gene. And it is also a component of the nuclear factor of activated T cells DNA-binding transcription complex. The NFATC1 gene is mapped on 18q23. Proteins belonging to this family of transcription factors play a central role in inducible gene transcription during immune response. NFATC1 was not detected in brain, liver, or kidney. NFATC1 is an inducible nuclear component which functions as a major molecular target for the immunosuppressive drugs such as cyclosporin A. The solution structure of the binary complex formed between the core DNA-binding domain of human NFATC1 and the 12-bp oligonucleotide duplex containing the ARRE2 DNA site from the IL2 promoter. Nfatc1 was expressed exclusively in mouse hair follicle stem cells, and using gain- and loss-of-function approaches, and Nfatc1 inhibited stem cell activation.

Application Notes

Optimal dilution of the NFAT2 antibody should be determined by the researcher.

Immunogen

A recombinant human protein corresponding to amino acids Q589-K652 (specific to isoforms A/B/C) was used as the immunogen for the NFAT2 antibody.

Storage

After reconstitution, the NFAT2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Related Products

   1.   View all NFAT2 antibodies

Cross
Bulk Quote Request Form
Name*:
Organization*:
Email*:
Phone Number*:
Catalog No.*:
Comments and Specifics(amount, formulation, etc.)*:
Validation code: Captchapackage Image


Can't read the image? click here to refresh.
    *required field

Your bulk quote request has been submitted successfully!

Please contact us if you have any questions.