• Tel: 858.663.9055
  • SeparatorEmail: info@nsjbio.com
  • Tel: 858.663.9055
  • Email: info@nsjbio.com
Order
Home >> Antibodies >> Neurexin 1 Antibody

Neurexin 1 Antibody (RQ4306)

NSJ bio Image Pdf Image
  Catalog No Formulation Size Price (USD)  
Image RQ4306 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 429
Bulk quote request
Western blot testing of human 1) U-87 MG and 2) SHG-4 cell lysate with Neurexin antibody at 0.5ug/ml. Predicted molecular weight ~162 kDa.
›
Western blot testing of human 1) U-87 MG and 2) SHG-4 cell lysate with Neurexin antibody at 0.5ug/ml. Predicted molecular weight ~162 kDa.
Western blot testing of human 1) U-87 MG and 2) U251 cell lysate with Neurexin antibody at 0.5ug/ml. Predicted molecular weight ~162 kDa.
Flow cytometry testing of human SH-SY5Y cells with Neurexin 1 antibody at 1ug/10^6 cells (blocked with goat sera); Red=cells alone, Green=isotype control, Blue=Neurexin 1 antibody.
Availability 1-3 business days
Species Reactivity Human
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Antigen affinity purified
Buffer Lyophilized from 1X PBS with 2% Trehalose and 0.025% sodium azide
UniProt P58400
Localization Cell membrane
Applications Western blot : 0.5-1ug/ml
Flow Cytometry : 1-3ug/10^6 cells
Direct ELISA : 0.1-0.5ug/ml
Limitations This Neurexin 1 antibody is available for research use only.
Review this product on BioCompare and get a $20 Amazon gift card

Related Products

  • Applications : WB, ELISA (peptide)
    Reactivity : Human
    Pred. Reactivity : Dog, Mouse, Rat

Description

Neurexin-1-alpha is a protein that in humans is encoded by the NRXN1 gene. This gene encodes a single-pass type I membrane protein that belongs to the neurexin family. Neurexins are cell-surface receptors that bind neuroligins to form Ca(2+)-dependent neurexin/neuroligin complexes at synapses in the central nervous system. This complex is required for efficient neurotransmission and is involved in the formation of synaptic contacts. Three members of this gene family have been studied in detail and are estimated to generate over 3,000 variants through the use of two alternative promoters (alpha and beta) and extensive alternative splicing in each family member. Recently, a third promoter (gamma) was identified for this gene in the 3' region. Mutations in this gene are associated with Pitt-Hopkins-like syndrome-2 and may contribute to susceptibility to schizophrenia.

Application Notes

Optimal dilution of the Neurexin 1 antibody should be determined by the researcher.

Immunogen

A recombinant human protein corresponding to amino acids D141-E294 was used as the immunogen for the Neurexin 1 antibody.

Storage

After reconstitution, the Neurexin 1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Related Products

   1.   View all Neurexin 1 antibodies

Cross
Bulk Quote Request Form
Name*:
Organization*:
Email*:
Phone Number*:
Catalog No.*:
Comments and Specifics(amount, formulation, etc.)*:
Validation code: Captchapackage Image


Can't read the image? click here to refresh.
    *required field

Your bulk quote request has been submitted successfully!

Please contact us if you have any questions.