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Home >> Antibodies >> NCAM Antibody / CD56

NCAM Antibody / CD56 [clone ERIC-1] (V7973)

  Catalog No Formulation Size Price (USD)  
Image V7973-100UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide 100 ug 519
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V7973-20UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide 20 ug 229
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V7973SAF-100UG 1 mg/ml in 1X PBS; BSA free, sodium azide free 100 ug 519
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IHC staining of FFPE human colon with NCAM antibody (clone ERIC-1). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
IHC staining of FFPE human colon with NCAM antibody (clone ERIC-1). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
SDS-PAGE analysis of purified, BSA-free NCAM antibody (clone ERIC-1) as confirmation of integrity and purity.
Availability 1-3 business days
Species Reactivity Human, Rat
Format Purified
Clonality Monoclonal (mouse origin)
Isotype Mouse IgG1, kappa
Clone Name ERIC-1
Purity Protein G affinity chromatography
UniProt P13591
Localization Cell surface
Applications Immunohistochemistry (FFPE) : 0.1-0.2ug/ml
Limitations This NCAM antibody is available for research use only.
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Description

This MAb reacts with an extracellular domain (close to transmembrane) of CD56/NCAM. Three isoforms of neural cell adhesion molecule (NCAM) are produced by differential splicing of the RNA transcript from a single gene. The 135kDa isoform is the basic molecule, which is glycosylated or sialylated to produce the mature species. Anti-CD56 recognizes two proteins of the neural cell adhesion molecule, the basic molecule expressed on most neuroectodermally derived tissues and neoplasms (e.g. retinoblastoma, medulloblastomas, astrocytomas, neuroblastomas, and small cell carcinomas). It is also expressed on some mesodermally derived tumors (rhabdomyosarcoma). Anti-CD56 plays an important role in the diagnosis of nodal and nasal NK/T-cell lymphomas.

Application Notes

Optimal dilution of the NCAM antibody should be determined by the researcher.

Immunogen

A recombinant human protein was used as the immunogen for this NCAM antibody.

Storage

Store the NCAM antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

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