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- Tel: 858.663.9055
- Email: info@nsjbio.com
Zinc finger genes that encode metal-binding proteins are transcriptional regulators of other genes. Myeloid zinc finger 1 (MZF-1), also designated zinc finger protein 42, and transcription factor ZBP-89, also designated zinc finger protein 148, belong to the Kruppel C2H2-type zinc-finger protein family. The gene encoding for the MZF-1 protein maps to chromosome 19q13.43 while the gene encoding for ZBP-89 is localized on chromosome 3q21. These proteins are nuclear proteins involved in the regulation of transcriptional events. MZF-1 regulates transcription during hemopoietic development and plays a role in myeloid cell differentiation. MZF-1 regulates the CD34 promoter in a tissue-specific manner. MZF-1 and FHL3 can form a complex of high molecular mass with other proteins in the nucleus. It is induced by retinoic acid and is primarily expressed in differentiating myeloid cells.
Optimal dilution of the Myeloid zinc finger 1 antibody should be determined by the researcher.
A recombinant partial protein sequence (within amino acids 37-128) from the human protein was used as the immunogen for the Myeloid zinc finger 1 antibody.
Aliquot the Myeloid zinc finger 1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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