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Home >> Antibodies >> Myelin PLP Antibody

Myelin PLP Antibody [clone PLP1/4259] (V8681)

  Catalog No Formulation Size Price (USD)  
Image V8681-100UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide 100 ug 519
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V8681-20UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide 20 ug 229
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V8681SAF-100UG 1 mg/ml in 1X PBS; BSA free, sodium azide free 100 ug 519
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IHC staining of FFPE human brain with Myelin PLP antibody (clone PLP1/4259). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
SDS-PAGE analysis of purified, BSA-free Myelin PLP antibody (clone PLP1/4259) as confirmation of integrity and purity.
Availability 1-3 business days
Species Reactivity Human
Format Purified
Clonality Monoclonal (mouse origin)
Isotype Mouse IgG2a
Clone Name PLP1/4259
Purity Protein G affinity chromatography
UniProt P60201
Localization Membrane
Applications Immunohistochemistry (FFPE) : 1-2ug/ml for 30 minutes at RT
Limitations This Myelin PLP antibody is available for research use only.
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  • Applications : WB, ELISA
    Reactivity : Human
    Pred. Reactivity : Mouse, Bovine, Pig, Primate, Chicken, Rabbit

Description

Proteolipid protein (PLP) is the major myelin protein of the CNS and plays an important role in the formation and maintenance of myelin. PLP may play a role in the compaction and stabilization of myelin sheaths, as well as in oligodendrocyte development and axonal survival. Mutations in PLP gene can lead to dysmyelinating diseases.

Application Notes

Optimal dilution of the Myelin PLP antibody should be determined by the researcher.

Immunogen

A synthetic peptide from the C terminal region of the human protein was used as the immunogen for the Myelin PLP antibody. The epitope has been mapped to amino acids GRGTKF.

Storage

Store the Myelin PLP antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

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