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Home >> Antibodies >> MUT Antibody

MUT Antibody (R32601)

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  Catalog No Formulation Size Price (USD)  
Image R32601 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 429
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Western blot testing of 1) rat kidney and 2) human 22RV1 lysate with MUT antibody. Predicted molecular weight ~83 kDa.
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Western blot testing of 1) rat kidney and 2) human 22RV1 lysate with MUT antibody. Predicted molecular weight ~83 kDa.
IHC staining of FFPE human intestinal cancer with MUT antibody. HIER: boil tissue sections in pH6, 10mM citrate buffer, for 20 min and allow to cool before testing.
IHC staining of FFPE human lung cancer with MUT antibody. HIER: boil tissue sections in pH6, 10mM citrate buffer, for 20 min and allow to cool before testing.
IHC staining of FFPE human breast cancer with MUT antibody. HIER: boil tissue sections in pH6, 10mM citrate buffer, for 20 min and allow to cool before testing.
Availability 1-3 business days
Species Reactivity Human, Rat
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Antigen affinity
Buffer Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide
UniProt P22033
Applications Western blot : 0.1-0.5ug/ml
Immunohistochemistry (FFPE) : 0.5-1ug/ml
Limitations This MUT antibody is available for research use only.
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Description

Methylmalonyl-CoA mutase (MUT) is a mitochondrial enzyme that catalyzes the isomerization of methylmalonyl-CoA to succinyl-CoA. This gene is mapped to 6p12.3. MUT requires a vitamin B12-derived prosthetic group, adenosylcobalamin (commonly referred to as AdoCbl), to function. And the product of this enzyme, succinyl-CoA, is a key molecule of the TCA cycle.

Application Notes

Optimal dilution of the MUT antibody should be determined by the researcher.

Immunogen

Amino acids 33-65 (LHQQQPLHPEWAALAKKQLKGKNPEDLIWHTPE-human) were used as the immunogen for the MUT antibody.

Storage

After reconstitution, the MUT antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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