- Tel: 858.663.9055
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
MUSK Antibody (F50653)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
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F50653-0.4ML | In 1X PBS, pH 7.4, with 0.09% sodium azide | 0.4 ml | 399 | |
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F50653-0.08ML | In 1X PBS, pH 7.4, with 0.09% sodium azide | 0.08 ml | 185 |
| Availability | 1-3 business days |
| Species Reactivity | Human, Mouse |
| Format | Purified |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit Ig |
| Purity | Purified |
| UniProt | O15146 |
| Applications | Western blot : 1:1000 Flow Cytometry : 1:10-1:50 Immunofluorescence : 1:10-1:50 |
| Limitations | This MUSK antibody is available for research use only. |
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MuSK activates signaling cascades responsible for many aspects of synapse formation, including the organization of the postsynaptic membrane, synapse-specific transcription, and presynaptic differentiation. MuSK also mediates agrin-induced aggregation of acetylcholine receptors at the mature vertebrate neuromuscular junction and also during synapse formation. It has been shown that a majority of AChR Ab-seronegative myasthenia gravis patients possess serum autoantibodies against MuSK.
Titration of the MUSK antibody may be required due to differences in protocols and secondary/substrate sensitivity.
This MUSK antibody was produced from rabbits immunized with human MUSK recombinant protein.
Aliquot the MUSK antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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