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Home >> Antibodies >> Mucin-6 Antibody

Mucin-6 Antibody [clone MUCN6-1] (V7132)

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  Catalog No Formulation Size Price (USD)  
Image V7132-100UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide 100 ug 519
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V7132-20UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide 20 ug 229
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V7132SAF-100UG 1 mg/ml in 1X PBS; BSA free, sodium azide free 100 ug 519
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V7132IHC-7ML Prediluted in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide; *For IHC use only* 7 ml 519
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IHC testing of FFPE human gastric carcinoma with Mucin-6 antibody (clone MUCN6-1). FFPE testing requires sections to be boiled in pH 9 10mM Tris with 1mM EDTA for 10-20 minutes, followed by cooling at RT for 20 minutes, prior to staining.
IHC testing of FFPE human gastric carcinoma with Mucin-6 antibody (clone MUCN6-1). FFPE testing requires sections to be boiled in pH 9 10mM Tris with 1mM EDTA for 10-20 minutes, followed by cooling at RT for 20 minutes, prior to staining.
Availability 1-3 business days
Species Reactivity Human
Format Purified
Clonality Monoclonal (mouse origin)
Isotype Mouse IgG1, kappa
Clone Name MUCN6-1
Purity Protein G affinity chromatography
UniProt Q6W4X9
Localization Cytoplasmic & secreted
Applications Immunohistochemistry (FFPE) : 2-4ug/ml for 30 min at RT
Prediluted IHC only format : incubate for 30 min at RT (1)
Limitations This Mucin-6 antibody is available for research use only.
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Description

Mucin 6 may provide a mechanism for modulation of the composition of the protective mucus layer related to acid secretion or the presence of bacteria and noxious agents in the lumen. Plays an important role in the cytoprotection of epithelial surfaces and are used as tumor markers in a variety of cancers. May play a role in epithelial organogenesis. Highest expression seen in the stomach and gall bladder, with lower expression in the terminal ileum and right colon. [UniProt]

Application Notes

Titering of the Mucin-6 antibody may be required for optimal performance.

1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

Immunogen

Recombinant human protein was used as the immunogen for the Mucin-6 antibody.

Storage

Store the Mucin-6 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

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