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Home >> Antibodies >> MPO Antibody / Myeloperoxidase

MPO Antibody / Myeloperoxidase [clone AOCF-13] (RQ5109)

  Catalog No Formulation Size Price (USD)  
Image RQ5109 Antibody in PBS with 0.02% sodium azide, 50% glycerol and 0.4-0.5mg/ml BSA 100 ul 429
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Western blot testing of human HL60 cell lysate with MPO antibody. Expected molecular weight: 59-64 kDa (alpha chain, may be observed at higher molecular weights due to glycosylation), 150+ kDa (glycosylated mature form).
Availability 1-2 weeks
Species Reactivity Human
Format Purified
Clonality Rabbit Monoclonal
Isotype Rabbit IgG
Clone Name AOCF-13
Purity Affinity purified
UniProt P05164
Applications Western blot : 1:500-1:2000
Limitations This MPO antibody is available for research use only.
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Description

Myeloperoxidase (MPO) is a heme protein synthesized during myeloid differentiation that constitutes the major component of neutrophil azurophilic granules. Produced as a single chain precursor, myeloperoxidase is subsequently cleaved into a light and heavy chain. The mature myeloperoxidase is a tetramer composed of 2 light chains and 2 heavy chains. This enzyme produces hypohalous acids central to the microbicidal activity of neutrophils. [RefSeq]

Application Notes

Optimal dilution of the MPO antibody should be determined by the researcher.

Immunogen

A synthetic peptide specific to human Myeloperoxidase was used as the immunogen for the MPO antibody.

Storage

Store the MPO antibody at -20oC.

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