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- Tel: 858.663.9055
- Email: info@nsjbio.com
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Myeloperoxidase is a mammalian phagocyte hemoprotein thought to primarily mediate host defense reactions. It is abundantly expressed in neutrophils and secreted during their activation. MPO is part of the host defense system of human polymorphonuclear leukocytes, responsible for microbicidal activity against a wide range of organisms. Located in the nucleus as well as in the cytoplasm, intranuclear MPO may help to protect DNA against damage resulting from oxygen radicals produced during myeloid cell maturation and function.
The stated application concentrations are suggested starting points. Titration of the MPO antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Human partial recombinant protein (AA 406-745) was used as the immunogen for this MPO antibody.
After reconstitution, the MPO antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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