- Tel: 858.663.9055
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
Mouse CD11b Antibody / MAC-1 / ITGAM (R32580)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
 |
R32580 | 0.5mg/ml if reconstituted with 0.2ml sterile DI water | 100 ug | 429 |
|
| Availability | 1-3 business days |
| Species Reactivity | Mouse |
| Format | Antigen affinity purified |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit IgG |
| Purity | Antigen affinity |
| Buffer | Lyophilized from 1X PBS with 2.5% BSA and 0.025% sodium azide |
| UniProt | P05555 |
| Localization | Cell membrane, cytoplasm |
| Applications | Western blot : 0.5-1ug/ml |
| Limitations | This mouse CD11b antibody is available for research use only. |
|
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Integrin alpha M (ITGAM) is one protein subunit that forms the heterodimeric integrin alpha-M beta-2 (aM/b2) molecule, also known as macrophage-1 antigen (Mac-1) or cluster of differentiation molecule 11b (CD11b). It is mapped to 16p11.2. ITGAM/CD11b has a role in vascular repair after mechanical arterial injury. It is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. What's more, ITGAM probably recognizes the R-G-D peptide in C3b, and it is also a receptor for fibrinogen, factor X and ICAM1.
Optimal dilution of the mouse CD11b antibody should be determined by the researcher.
A mouse recombinant protein corresponding to amino acids E260-T360 was used as the immunogen for the mouse CD11b antibody.
After reconstitution, the mouse CD11b antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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