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Home >> Antibodies >> MCL1 Antibody

MCL1 Antibody (F43180)

  Catalog No Formulation Size Price (USD)  
Image F43180-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 399
Image
F43180-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 185
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MCL1 antibody western blot analysis in Y79 lysate. Predicted molecular weight: 37/29 kDa (isoforms 1/2).
MCL1 antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue.
Availability 1-3 business days
Species Reactivity Human
Predicted Reactivity Rat
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Antigen affinity
UniProt Q07820
Applications Western blot : 1:1000
IHC (Paraffin) : 1:10-1:50
Limitations This MCL1 antibody is available for research use only.
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Description

This gene encodes an anti-apoptotic protein, which is a member of the Bcl-2 family. Alternative splicing results in multiple transcript variants. The longest gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene products (isoform 2 and isoform 3) promote apoptosis and are death-inducing.

Application Notes

Titration of the MCL1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A portion of amino acids 217-245 from the human protein was used as the immunogen for this MCL1 antibody.

Storage

Aliquot the MCL1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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