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- Email: info@nsjbio.com
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This gene encodes an anti-apoptotic protein, which is a member of the Bcl-2 family. Alternative splicing results in multiple transcript variants. The longest gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene products (isoform 2 and isoform 3) promote apoptosis and are death-inducing.
Titration of the MCL1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
A portion of amino acids 217-245 from the human protein was used as the immunogen for this MCL1 antibody.
Aliquot the MCL1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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