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Home >> Antibodies >> MAP2 Antibody / Microtubule-associated protein 2

MAP2 Antibody / Microtubule-associated protein 2 [clone MAP2/7673] (V4938)

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  Catalog No Formulation Size Price (USD)  
Image V4938-100UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide 100 ug 519
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V4938-20UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide 20 ug 229
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V4938SAF-100UG 1 mg/ml in 1X PBS; BSA free, sodium azide free 100 ug 519
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IHC staining of FFPE human brain tissue with MAP2 antibody (clone MAP2/7673). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
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IHC staining of FFPE human brain tissue with MAP2 antibody (clone MAP2/7673). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
IHC staining of FFPE human brain tissue with MAP2 antibody (clone MAP2/7673). Inset: PBS used in place of primary Ab (secondary Ab negative control). HIER: boil tissue sections in pH 9 10mM Tris with 1mM EDTA for 20 min and allow to cool before testing.
SDS-PAGE analysis of purified, BSA-free MAP2 antibody (clone MAP2/7673) as confirmation of integrity and purity.
Availability 1-3 business days
Species Reactivity Human
Format Purified
Clonality Monoclonal (mouse origin)
Isotype Mouse IgG1, kappa
Clone Name MAP2/7673
Purity Protein A/G affinity
UniProt P11137
Localization Cytoplasm
Applications Immunohistochemistry (FFPE) : 1-2ug/ml for 30 min at RT
Limitations This MAP2 antibody is available for research use only.
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Description

Microtubules, the primary component of the cytoskeletal network, interact with proteins called microtubule-associated proteins (MAPs). The microtubule-associated proteins can be divided into two groups, structural and dynamic. The structural microtubule-associated proteins, MAP-1A, MAP-1B, MAP-2A, MAP-2B and MAP-2C, stimulate tubulin assembly, enhance microtubule stability and influence the spatial distribution of microtubules within cells. Both MAP-1 and, to a greater extent, MAP-2 have been implicated as agents of microtubule depolymerization by suppressing the dynamic instability of the microtubules. The suppression of microtubule dynamic instability by the MAP proteins is thought to be associated with phosphorylation of the MAPs.

Application Notes

Optimal dilution of the MAP2 antibody should be determined by the researcher.

Immunogen

A recombinant partial protein sequence (within amino acids 1500-1700) from the human protein was used as the immunogen for the MAP2 antibody.

Storage

Aliquot the MAP2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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