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Home >> Antibodies >> Mannose-binding protein C Antibody / MBL2

Mannose-binding protein C Antibody / MBL2 (RQ8126)

  Catalog No Formulation Size Price (USD)  
Image RQ8126 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 429
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Flow cytometry testing of fixed and permeabilized human HepG2 cells with Mannose-binding protein C antibody at 1ug/million cells (blocked with goat sera); Red=cells alone, Green=isotype control, Blue= Mannose-binding protein C antibody.
Western blot testing of human HCCT cell lysate with Mannose-binding protein C antibody. Predicted molecular weight ~26 kDa.
Availability 1-3 business days
Species Reactivity Human
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Antigen affinity purified
Buffer Lyophilized from 1X PBS with 2% Trehalose
UniProt P11226
Applications Western blot : 0.5-1ug/ml
Flow cytometry : 1-3ug/million cells
Direct ELISA : 0.1-0.5ug/ml
Limitations This Mannose-binding protein C antibody is available for research use only.
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Description

This gene encodes the soluble mannose-binding lectin or mannose-binding protein found in serum. The protein encoded belongs to the collectin family and is an important element in the innate immune system. The protein recognizes and binds to mannose and N-acetylglucosamine on many microorganisms, including bacteria, yeast, and viruses including influenza virus, HIV and SARS-CoV. This binding activates the classical complement pathway. Deficiencies of this gene have been associated with susceptibility to autoimmune and infectious diseases.

Application Notes

Optimal dilution of the Mannose-binding protein C antibody should be determined by the researcher.

Immunogen

E. coli-derived recombinant human protein (amino acids E21-I248) was used as the immunogen for the Mannose-binding protein C antibody.

Storage

After reconstitution, the Mannose-binding protein C antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

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