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- Tel: 858.663.9055
- Email: info@nsjbio.com
Mitotic spindle assembly checkpoint protein MAD1 is a protein that in humans is encoded by the MAD1L1 gene. It is mapped to 7p22.3. MAD1 is a component of the mitotic spindle-assembly checkpoint that prevents the onset of anaphase until all chromosome are properly aligned at the metaphase plate. It can function as a homodimer. It localizes to the centrosome during metaphase and to the spindle midzone and the midbody during anaphase and telophase. MAD1 may also play a role in cell cycle control and tumor suppression.
The stated application concentrations are suggested starting amounts. Titration of the MAD1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
Human partial recombinant protein (AA 362-632) was used as the immunogen for this MAD1 antibody.
After reconstitution, the MAD1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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