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Home >> Antibodies >> LGALS13 Antibody / Galectin 13

LGALS13 Antibody / Galectin 13 [clone PP13/1165] (V3339)

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  Catalog No Formulation Size Price (USD)  
Image V3339-100UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide 100 ug 519
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V3339-20UG 0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide 20 ug 229
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V3339SAF-100UG 1 mg/ml in 1X PBS; BSA free, sodium azide free 100 ug 519
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IHC testing of FFPE human placenta with LGALS13 antibody (clone PP13/1165). Required HIER: boil tissue sections in 10mM Tris with 1mM EDTA, pH 9 or 10mM Citrate buffer, pH 6, for 10-20.
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IHC testing of FFPE human placenta with LGALS13 antibody (clone PP13/1165). Required HIER: boil tissue sections in 10mM Tris with 1mM EDTA, pH 9 or 10mM Citrate buffer, pH 6, for 10-20.
SDS-PAGE Analysis of Purified, BSA-Free LGALS13 Antibody (clone PP13/1165). Confirmation of Integrity and Purity of the Antibody.
Availability 1-3 business days
Species Reactivity Human
Format Purified
Clonality Monoclonal (mouse origin)
Isotype Mouse IgG2b, kappa
Clone Name PP13/1165
Purity Protein G affinity chromatography
UniProt Q9UHV8
Localization Cytoplasmic, cell surface
Applications ELISA (order BSA/sodium azide-free format for coating) :
Immunohistochemistry (FFPE) : 0.5-1ug/ml for 30 min at RT
Limitations This LGALS13 antibody is available for research use only.
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Description

It recognizes a 32kDa protein, which is identified as homodimer of LGALS13/Galectin 13 (also known as PP13). Galectins are a family of soluble β-galactoside-binding lectins that modulate cell-to-cell adhesion and cell-to-extracellular matrix (ECM) interactions and play a role in tumor progression, pre-mRNA splicing and apoptosis. One such member, LGALS13, is a 139 amino acid protein that contains one galectin domain. Possessing lysophospholipase activity, LGALS13 exists as a disulfide-linked homodimer. LGALS13 is suggested to have a developmental role in the placenta and may display immunobiological activity in feto-maternal blood-spaces. Screening for LGALS13/Galectin 13 in maternal serum during the first trimester of pregnancy may serve as a diagnostic marker to predict preterm pre-eclampsia.

Application Notes

Titering of the LGALS13 antibody may be required for optimal performance.

Immunogen

A human partial recombinant protein corresponding to amino acids 23-134 was used as the immunogen for the LGALS13 antibody.

Storage

Store the LGALS13 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

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