- Tel: 858.663.9055
Email: info@nsjbio.com
- Tel: 858.663.9055
- Email: info@nsjbio.com
Leucyl tRNA synthetase Antibody / LARS (RQ4955)
Email: info@nsjbio.com
| Catalog No | Formulation | Size | Price (USD) | ||
|---|---|---|---|---|---|
 |
RQ4955 | 0.5mg/ml if reconstituted with 0.2ml sterile DI water | 100 ug | 429 |
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| Availability | 1-3 business days |
| Species Reactivity | Human, Mouse, Rat |
| Format | Antigen affinity purified |
| Clonality | Polyclonal (rabbit origin) |
| Isotype | Rabbit IgG |
| Purity | Antigen affinity purified |
| Buffer | Lyophilized from 1X PBS with 2% Trehalose and 0.025% sodium azide |
| UniProt | Q9P2J5 |
| Applications | Western blot : 0.5-1ug/ml Direct ELISA : 0.1-0.5ug/ml |
| Limitations | This Leucyl tRNA synthetase antibody is available for research use only. |
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Leucyl-tRNA synthetase, cytoplasmic is an enzyme that in humans is encoded by the LARS gene. This gene is mapped to 5q32. It encodes a cytosolic leucine-tRNA synthetase, a member of the class I aminoacyl-tRNA synthetase family. The encoded enzyme catalyzes the ATP-dependent ligation of L-leucine to tRNA(Leu). It is found in the cytoplasm as part of a multisynthetase complex and interacts with the arginine tRNA synthetase through its C-terminal domain. A mutation in this gene was found in affected individuals with infantile liver failure syndrome 1. Alternatively spliced transcript variants of this gene have been observed.
Optimal dilution of the Leucyl tRNA synthetase antibody should be determined by the researcher.
Amino acids Q628-Q855 from the human protein were used as the immunogen for the Leucyl tRNA synthetase antibody.
After reconstitution, the Leucyl tRNA synthetase antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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