• Tel: 858.663.9055
  • SeparatorEmail: info@nsjbio.com
  • Tel: 858.663.9055
  • Email: info@nsjbio.com
Order
Home >> Antibodies >> LDLR Antibody / LDL Receptor

LDLR Antibody / LDL Receptor (RQ8038)

NSJ bio Image Pdf Image
  Catalog No Formulation Size Price (USD)  
Image RQ8038 0.5mg/ml if reconstituted with 0.2ml sterile DI water 100 ug 429
Bulk quote request
Flow cytometry testing of fixed and permeabilized human MCF7 cells with LDLR antibody at 1ug/million cells (blocked with goat sera); Red=cells alone, Green=isotype control, Blue= LDLR antibody.
›
Flow cytometry testing of fixed and permeabilized human MCF7 cells with LDLR antibody at 1ug/million cells (blocked with goat sera); Red=cells alone, Green=isotype control, Blue= LDLR antibody.
Western blot testing of human HeLa cell lysate with LDLR antibody. Expected molecular weight: 95-160 kDa depending on glycosylation level.
Availability 1-3 business days
Species Reactivity Human
Format Antigen affinity purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit IgG
Purity Antigen affinity purified
Buffer Lyophilized from 1X PBS with 2% Trehalose
UniProt P01130
Applications Western blot : 0.5-1ug/ml
Flow cytometry : 1-3ug/million cells
Direct ELISA : 0.1-0.5ug/ml
Limitations This LDLR antibody is available for research use only.
Review this product on BioCompare and get a $20 Amazon gift card

Related Products

Description

In humans, the LDL receptor protein is encoded by the LDLR gene on chromosome 19. It is mapped to 19p13.2. The low absorbance lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. Low absorbance lipoprotein (LDL) is normally bound at the cell membrane and taken into the cell ending up in lysosomes where the protein is degraded and the cholesterol is made available for repression of microsomal enzyme 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, the rate-limiting step in cholesterol synthesis. At the same time, a reciprocal stimulation of cholesterol ester synthesis takes place. Mutations in this gene cause the autosomal dominant disorder, familial hypercholesterolemia. Alternate splicing results in multiple transcript variants.

Application Notes

Optimal dilution of the LDLR antibody should be determined by the researcher.

Immunogen

E. coli-derived recombinant human protein (amino acids A705-A860) was used as the immunogen for the LDLR antibody.

Storage

After reconstitution, the LDLR antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Related Products

   1.   View all LDLR antibodies

Cross
Bulk Quote Request Form
Name*:
Organization*:
Email*:
Phone Number*:
Catalog No.*:
Comments and Specifics(amount, formulation, etc.)*:
Validation code: Captchapackage Image


Can't read the image? click here to refresh.
    *required field

Your bulk quote request has been submitted successfully!

Please contact us if you have any questions.