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Home >> Antibodies >> Lamin B2 Antibody

Lamin B2 Antibody (F49833)

  Catalog No Formulation Size Price (USD)  
Image F49833-0.4ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.4 ml 399
Image
F49833-0.08ML In 1X PBS, pH 7.4, with 0.09% sodium azide 0.08 ml 185
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Western blot analysis of Lamin B2 antibody and Y79 lysate
Availability 1-3 business days
Species Reactivity Human
Format Purified
Clonality Polyclonal (rabbit origin)
Isotype Rabbit Ig
Purity Purified
UniProt Q03252
Applications Western blot : 1:1000
Limitations This Lamin B2 antibody is available for research use only.
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Description

The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Lamin B2 is one of the two B type proteins, B2.

Application Notes

Titration of the Lamin B2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Immunogen

A portion of amino acids 476-504 from the human protein was used as the immunogen for this Lamin B2 antibody.

Storage

Aliquot the Lamin B2 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

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